CAMBRIDGE, Mass. – For several years, a class of anti-diabetic drugs known as biguanides, has been associated with anti-cancer properties. A number of retrospective studies have shown that the widely used diabetes drug metformin can benefit some cancer patients.
CAMBRIDGE, Mass. – Using a new in vivo screening system, Whitehead Institute researchers have identified a protein in the serine biosynthesis pathway that is essential in estrogen receptor (ER)-negative breast cancer
Our laboratory focuses on identifying metabolic pathways that are altered in the transformed state, understanding how those pathways support transformation, and investigating the environmental, genetic and epigenetic contexts in which such pathways act.
